This article examines the primary interpretations of the “Little Horn” in Daniel 8, an apocalyptic symbol representing the Antichrist. Building on prior studies connecting Daniel’s visions of world empires—Babylon, Medo-Persia, Greece, and Rome—the author explores three main theological frameworks regarding the horn’s identity: the Preterist view (identifying the horn as the 2nd-century BC Seleucid king Antiochus IV Epiphanes), the Futurist view (seeing it as an end-time persecutor before Christ’s return), and the Historicist view (identifying it with the Roman State Church that evolved after the fall of Rome). The article dives deeply into the Historicist perspective, detailing the historical shift from early subordinationist Christology to post-Nicene Orthodoxy, the political influence of emperors like Constantine and Theodosius I, and how legislative actions like the Edict of Thessalonica established state-sponsored religious authority.